Inject intramuscularly deep into the deltoid muscle in adults and older children or anterolateral aspect of upper thigh (mid-thigh laterally) in younger children. The vaccine should not be injected into the gluteal areas where there may be a major nerve trunk.
A sterile needle and a sterile syringe should be used for each injection. The vaccine should be visually inspected for any foreign particulate matter and/or variation of physical aspect prior to administration. In the event of either being observed, discard the vaccine.
Where administration of tetanus immunoglobulin is indicated (e.g., tetanus prone wound) the vaccine should be administered at a separate site, with separate needle and syringe.
Persons who have not completed primary immunization against tetanus, or whose immunization history is unknown or uncertain, should be immunized with tetanus toxoid. Full cycle of vaccinations plan is 0-1, 6-12 month. (Two initial doses in time intervals not shorter than 4-6 weeks, the third supplementary dose after 6 months to 1 year from the second vaccination). Booster vaccination, one dose every 10 years from the last vaccination.
TT may be given at the same time as BCG, measles, rubella, mumps, polio (OPV and IPV) Hepatitis B, Haemophilus influenza type b and yellow fever vaccines and vitamin A supplementation.