Shake well before withdrawing each dose to homogenize the suspension, avoid foaming. Discard if vaccine cannot be resuspended to a homogenous suspension.
Before injection, the skin over the site to be injected should be cleansed with a suitable germicide.
Inject intramuscularly deep into the deltoid muscle in adults and older children or anterolateral aspect of upper thigh (mid-thigh laterally) in younger children. The vaccine should not be injected into the gluteal areas where there may be a major nerve trunk.
A sterile needle and a sterile syringe should be used for each injection. The vaccine should be visually inspected for any foreign particulate matter and/or variation of physical aspect prior to administration. In the event of either being observed, discard the vaccine.